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Assessment
Tell us about your health history, activity and energy goals. Takes about 5 minutes.
Compounded MOTS-c
Made by your mitochondria. Prescribed for you.
A peptide studied for metabolism and how your body turns glucose and fat into energy. Reviewed by a licensed clinician, made for you by name in a U.S. pharmacy, and refilled automatically.
Always fresh. A new vial ships every month, on every plan. Longer plans are billed up front.
MOTS-c vial + injection suppliesClinician review + check-insMade from tested ingredientsFree shipping, ships monthly
Start my assessmentGet started$105/moAbout 5 minutes · Pause or cancel anytime · Full refund if not prescribed
Compounded drug, not FDA-approved. Prescription required; a licensed clinician decides if it's right for you.
Licensed U.S. pharmacyClinician-prescribedTested ingredientsFree shippingPause or cancel anytime
The energy protocol
MOTS-c · Injection
A metabolism peptide, made for your routine.
A small under-the-skin injection, with what you need in the box and a step-by-step guide.
Made for humans.Not "for research only." Compounded in a U.S.-licensed pharmacy from tested ingredients.
Clinician reviewedA licensed U.S. clinician reviews every order, and your full medication list, before anything is made.
Made for people who moveStudied for how muscles use fuel, and for exercise capacity in animal studies.
Ships to your doorFree shipping, one vial a month, included in your plan.
The metabolism pair
Pair it with your GLP-1 plan
Already on compounded semaglutide or tirzepatide with Bon? Ask your clinician about adding MOTS-c to your plan.
Clinician reviewedSeparate prescription
Start both today →Health shouldn't be complicated
How Bon works
1
ReviewedYour intake
U.S. licensedClinician
DecisionMOTS-c
✓Approved
Clinician review
A licensed U.S. clinician reviews your intake and decides if MOTS-c is right for you.
Your care teamWeek 2 check-in, how's the new routine going?
Good so far. Can my refills ship with my <span class="nw">GLP-1</span> order?
Auto refillsMessage anytime
Ongoing care
Your vial ships free with supplies and a how-to guide. A fresh vial ships each month, on every plan, and your care team is one message away for questions and adjustments.
See if you qualify →Quick online assessment · Private · Full refund if not prescribed
From the research
How MOTS-c works in the body
- 1
Made by your own mitochondria
MOTS-c is a rare kind of peptide: it's encoded in mitochondrial DNA, the separate set of genes inside your cells' power plants. Researchers first described it in 2015.
- 2
Glucose and fat as fuel
MOTS-c has been researched for metabolism, especially how cells take in glucose and use fat for energy. Studies link it to AMPK, the cell's built-in energy sensor.
- 3
Muscle and exercise capacity
In animal studies, MOTS-c was researched for how muscle cells handle glucose and for exercise capacity, including in older animals.
- 4
Metabolic health as we age
Natural MOTS-c levels tend to drop with age, so researchers are looking at its role in keeping metabolism healthy over time.
MOTS-cMitochondrial signal peptideMitochondriaWhere it's madeEnergy sensor (AMPK)NucleusEnergy-response genesGlucose & fatStudied for glucose useMuscleResearched in muscle cellsAgingMetabolic health with age
Based on published research, much of it in lab and animal studies. Individual results vary. MOTS-c is not FDA-approved for any use, and compounded medications have not been evaluated by the FDA for safety or effectiveness.
Straight from our members
Real people, real routines
“Honestly the easiest part of my week. I did the assessment on my lunch break, heard back from the care team the next day, and my order showed up faster than I expected. Anytime I have a question, a real person actually answers.”
“I've tried SO many different providers and none of them made things as straightforward as Bon.”
“My days are already really long and adding a doctor's visit on top was not it. Bon helped me get everything I needed in just a few minutes and it's been a gamechanger.”
“This peptide stuff was always confusing to me and every website made it look like a scam. But Bon helped answer my questions quickly and got my program started in under a day”
“I honestly spammed my provider with questions when I first started and they were always quick and helpful!”
“Peptides always felt like a science experiment to me with everything online being so shady. [Bon] helped me understand the whole process and I wish I found them sooner!”
Individual reviews reflect personal experiences and are not typical or guaranteed results.
Why get MOTS-c through Bon
Not all peptides are made the same way. Here's what you get with a prescription.
Research-chemical sites
Prescribed by a licensed clinician who sees your full med list
Made for you by name in a U.S. pharmacy
Injection supplies + how-to guide
Buy and figure it out yourself
Made from tested ingredients
Varies
Dispensed for personal use
Sold "for research only"
Care team to message
A fresh vial, on schedule
Metabolism is a long game, not a one-off. Your plan refills on its own, so you never have to reorder or wonder what's in the vial.
- Ships one month at a timeEven on Quarterly or Bi-annual, a fresh vial ships each month before you run out, free every time.
- Clinician check-insYour clinician reviews how it's going and adjusts your plan when needed.
- Same pharmacy, tested ingredientsEach vial is made for you by name from tested ingredients.
- Pause or cancel anytimeFrom your account, in a couple of taps. No calls, no contracts.
FAQ
Questions about MOTS-c
Still have questions? Message our care team.
If you're having a medical emergency, call 911. If you're in crisis, call or text 988 for the Suicide & Crisis Lifeline.
What is MOTS-c?+
MOTS-c is a peptide, a short chain of amino acids, that your body makes on its own. Unlike almost every other peptide, it's encoded in your mitochondrial DNA. It has been researched for metabolism, how the body uses glucose and fat for energy, and exercise capacity. At Bon it is prescribed by a licensed clinician and compounded by a licensed U.S. pharmacy.
Is MOTS-c FDA-approved?+
No. Compounded drugs, including compounded MOTS-c, are not FDA-approved. They are prepared by a licensed pharmacy for an individual patient with a prescription.
Can I legally get MOTS-c this way?+
In October 2026, HHS announced an interim policy (Federal Register 2026-22192) saying it won't take enforcement action against state-licensed pharmacies compounding certain peptides, including MOTS-c acetate as an injection, for individual patients when strict conditions are met. This is not FDA approval, and it may change. State rules can differ.
How is this different from research-chemical sites?+
Research-chemical sites sell powder labeled 'for research only,' with no prescription and no clinician. Bon's MOTS-c is prescribed for you, compounded by name in a licensed U.S. pharmacy from tested ingredients and shipped with what you need to take it.
Is MOTS-c a weight-loss treatment?+
No. MOTS-c is not prescribed for weight loss, and we don't make weight claims for it. It's been researched for metabolism and energy use. If weight is your main goal, ask about our GLP-1 plans.
Can I take it with my GLP-1?+
Many members ask. Adding MOTS-c to a semaglutide or tirzepatide plan means a separate prescription. Your clinician reviews each one on its own and decides if it's right for you.
How is it taken?+
As a small subcutaneous injection, just under the skin. Your clinician sets your dose and schedule from your assessment and can adjust it at check-ins.
What are the side effects, and who shouldn't use it?+
No completed human trials exist, so long-term effects are unknown. People report a faster or pounding heartbeat, redness or irritation where they inject, trouble sleeping, and fever. Because MOTS-c is studied for how the body handles glucose, tell your clinician if you take insulin or other diabetes medicine, including a GLP-1, or if you have heart-rhythm problems. It's not for anyone pregnant, trying to conceive or breastfeeding, or under 18. Tell your clinician about all medications and conditions.
I'm an athlete. Can I use MOTS-c?+
MOTS-c is named on the World Anti-Doping Agency's Prohibited List as a metabolic modulator (S4) and is banned at all times. USADA says a medical exemption is highly unlikely. If you're drug-tested, don't use it.
What if I am not prescribed?+
If your clinician decides MOTS-c is not right for you, you get a full refund.
How does the subscription work, and how fast does it ship?+
Pick Bi-annual ($105/mo, billed $630 every 6 months), Quarterly ($115/mo, billed $345 every 3 months) or Monthly ($129/mo). Longer plans are billed up front but still ship one vial a month, so it always arrives fresh. Every shipment goes out automatically before you run out, with free shipping. You can pause, skip or cancel anytime from your account.
MOTS-c, done properly
From $105/mo. Clinician review, tested ingredients and free shipping included.
Start my assessment →About 5 minutes · Pause or cancel anytime · Full refund if not prescribed