GLP-1 medications work in part by reducing appetite — which is the point. But eating considerably less also makes it harder to meet your daily nutrient needs. This is general nutrition guidance, not a claim that GLP-1 drugs cause deficiency; it is about eating well while you eat less.
Food first
The single best move is to make the food you do eat count: protein, vegetables, fruit, legumes, and whole grains pack far more nutrition per bite than processed options. When appetite is low, nutrient density matters more than ever.
That said, a few nutrients are worth keeping on your radar, and your clinician can advise whether supplementation makes sense for you.
Nutrients to watch
Vitamin B12
B12 supports nerve function and red-blood-cell formation, and adequate intake can be harder to maintain when you eat less — it is also worth attention for anyone on long-term acid-suppression or metformin [1]. Food sources include fish, meat, eggs, and dairy; fortified foods help if you eat less animal protein.
Vitamin D and calcium
Rapid weight loss can affect bone health, so vitamin D and calcium are a sensible pair to be mindful of [2][3]. Many people don't get enough vitamin D from food alone, and calcium needs rise with age. Dairy, fortified plant milks, leafy greens, and sensible sun exposure all contribute.
Magnesium
Magnesium supports hundreds of processes in the body, and low intake is common when overall calories drop [4]. Nuts, seeds, legumes, whole grains, and leafy greens are good sources.
A sensible approach
- Build meals around nutrient-dense, protein-forward foods.
- Don't reach for a cabinet of pills — target what you actually need.
- Ask your care team before adding supplements, especially if you take other medications.
The NIH Office of Dietary Supplements fact sheets linked below are authoritative references for requirements and food sources.
Care that includes the whole picture
Bon Health programs include messaging with a care team that can talk through nutrition alongside your medication. Explore compounded semaglutide from $120/month or compounded tirzepatide from $170/month.
This article is for general education and is not medical advice. It does not replace the judgment of a licensed clinician. Compounded medications are not FDA-approved. Always talk with your healthcare provider before starting, changing, or stopping any medication.